Information & Tips

CIP cleaning: procedure, cleaning agents and the correct parameters

Reviewed by Eco-Nova GmbH · Last updated 16 October 2026 · 5 mins’ read time

Stainless steel tank with pipework in a production plant

Key points at a glance

CIP (Cleaning in Place) involves cleaning tanks, pipework and plant without dismantling them. Cleaning solutions are circulated through the system. Typical steps include pre-rinsing, an alkaline clean to remove grease and protein, an acidic clean to remove limescale and mineral deposits, and rinsing. The result depends on the chemicals used, temperature, duration and flow rate. Eco-Nova supplies the cleaning agents and agrees the parameters with you during the consultation.

Key messages

  • CIP cleans closed systems without the need for dismantling, automatically and consistently.
  • Alkaline cleaners dissolve grease and protein, whilst acidic cleaners dissolve limescale, milk scale and mineral deposits.
  • CIP cleaning agents must produce little foam, be easy to rinse off and be compatible with stainless steel and seals.
  • The chemistry, temperature, time and flow must all be right. Otherwise, deposits will remain in spray shadows and dead zones.

Contents

Where liquids, pastes or bulk materials pass through enclosed systems, manual cleaning is virtually impossible: in tanks, pipework, heat exchangers, mixers and filling systems. This is where CIP comes into play – Cleaning in Place, i.e. cleaning whilst the equipment is in operation. The system remains fully assembled; cleaning solutions are pumped through pipes and distributed into containers via spray heads. This saves time, ensures that the cleaning process is reproducible and allows it to be documented.

CIP is best known in the food, drink and dairy industries. However, it is also used in pharmaceutical and cosmetics production, in the chemical industry, and in the manufacture of paints, varnishes and adhesives.

This is how a CIP clean is carried out

Step Purpose A typical remedy
1. Pre-rinse Rinse out any large bits of food Water, often reclaimed wash water
2. Alkaline cleaning Remove grease, protein, sugar and organic deposits alkaline cleaner, usually used at elevated temperatures
3. Rinsing in between Rinse out all the lye Water
4. Acidic cleaning Removing limescale, milk scale, beer scale and mineral deposits acidic cleaner
5. Rinsing in between Rinse out all the acid thoroughly Water
6. Disinfection (if necessary) Kill germs Disinfectant or hot water
7. Final rinse Hand over the plant to production without leaving any residue Product-grade water

The steps required depend on the product and the plant. For light soiling, alkaline cleaning is sometimes sufficient. For heavy mineral deposits, the acidic stage is used more frequently. Some systems run the cleaning solution through just once (single-pass cleaning), whilst others collect it in tanks and reuse it several times (batch cleaning).

The four factors: chemistry, temperature, time and flow

The same applies to CIP: Sinner’s Circle. Instead of a brush and high-pressure jet, the flow of water takes care of the mechanical part here.

  • Chemistry: Cleaning agent type and concentration. CIP systems often control the concentration based on the solution’s conductivity.
  • Temperature: Many coatings come away much more easily when warm. However, temperatures that are too high can also cause the protein to burn.
  • Time: the contact time per step. If you save time, you often have to compensate by adjusting the concentration or temperature.
  • Mechanics (Fluid dynamics): In pipework, a turbulent flow is required. In tanks, the spray heads must reach all surfaces. Otherwise, deposits will remain in the spray shadow, dead zones and branch points.

What a CIP cleaner must be able to do

  • Low-foaming: Foam interferes with pumps and spray heads and prevents the solution from wetting the surface.
  • Easy to rinse off: No residues must enter the product.
  • Compatible with materials: with stainless steel, seals and plastics in the plant.
  • Temperature-stable: The effect must be maintained at the process temperature.
  • Adjustable and measurable: so that the system can control the concentration reliably.
  • Evidence: In the food and pharmaceutical sectors, for example, certificates of suitability.
  • Wastewater: Alkalis and acids usually need to be neutralised before discharge.

Where Eco-Nova can help

We focus on the cleaning stages. Disinfectants are not part of our product range. The factor Chemistry We supply them ourselves: we have been developing and manufacturing our cleaning agents in Schüttorf for over 30 years, in containers up to 1,000-litre IBCs. As we manufacture the products ourselves, we can tailor our cleaning agents to the requirements of your CIP system, for example in terms of foaming behaviour, concentration or temperature range. The following might be suitable for the individual steps, for example:

Task Typical surfacing materials Might be suitable
Alkaline cleaning burnt-on residues, protein, fat, food scraps Ultranova
highly alkaline, characterised by
Acid cleaning of pipework and tanks Limescale, mineral deposits, rust Novascal
coloured, marked; the colour-coding indicates the progress of the cleaning
Acid cleaning in food processing plants Limescale, rust, mineral deposits Meganova
acid-resistant; with NSF or ISEGA certification
Circuit cleaning in the non-food industry Oils, greases, pigments, light adhesive residues Microsolv Plus
low-foaming, dilutable; according to the MSDS, no hazard pictogram
Stubborn deposits, spray marks, dead spots burnt-on or cracked coatings individual, during the consultation

These suggestions are a starting point. We will work with you during the consultation to determine which cleaner, concentration and temperature are best suited to your plant and your product, carrying out tests on your plant.

Mechanics, temperature and time are located on your premises. We can offer advice on this:

  • We’ll work with you to identify which deposits are forming where and which step is required to remove them.
  • We test cleaning agents and concentrations on your plant and compare them with your current range.
  • We show where time, temperature or concentration can be adjusted without compromising the result.
  • For parts that are not reached by the CIP system – such as spray heads, seals or removed fittings – we can find the right cleaning agent for manual cleaning.
  • If there isn’t yet a suitable cleaner for your requirements, we will develop a bespoke formula (Tailor-made).
  • We can provide documentation such as NSF or ISEGA certificates and declarations regarding SVHCs and REACH on request. For more information: Compliance and Certificates.

Common problems and what lies behind them

  • The surfaces remain unchanged despite the programme: Often the flow isn’t right, there are spray shadows, or the temperature is too low.
  • Foam in the system: The detergent is not low-foaming, or product residue foams up during the pre-rinse.
  • Limescale and mineral deposits build up: The acid cycle isn’t running often enough, or the water is very hard.
  • Burnt egg white in heating elements: Excessively high temperatures during the alkaline stage or production runs that are too long.
  • High consumption of water, chemicals and energy: It is worth taking a look at batch cleaning, recovery and optimised parameters.

Always follow the instructions in the safety data sheet. Alkaline and acidic CIP cleaners are often classified as corrosive and require the use of protective equipment as specified in the safety data sheet. The safety data sheet is available on request to existing customers and to customers who have received a sample or attended a demonstration.

Is your CIP cleaning taking too long, using too much cleaning agent or leaving a residue? Tell us about your plant, product and your current cleaning programme. Our technical advisers will recommend a cleaning agent, put together some samples and, if you wish, visit you on site.

Free consultation

Together, we’ll solve your cleaning problem

Tell us about the type of contamination and the surface – our technical advisers will recommend the right solution. Samples are free of charge.

Would you prefer to speak on the phone? 05923 99 36 0

FAQ

Frequently Asked Questions

What does CIP cleaning mean?
CIP stands for Cleaning in Place. Tanks, pipework and plant are cleaned without being dismantled. Cleaning solutions are circulated through the system or distributed via spray heads.
What are the steps involved in a CIP clean?
The typical process involves a pre-rinse, an alkaline wash, an intermediate rinse, an acidic wash, an intermediate rinse, disinfection if required, and a final rinse. The steps required depend on the product and the plant.
When should I use an alkaline cleaner and when an acidic one?
Alkaline cleaners remove organic deposits such as fat, protein and sugar. Acidic cleaners remove mineral deposits such as limescale, milk scale or beer scale. Many systems require both.
Why does a CIP cleaner need to produce little foam?
Foam interferes with pumps and spray heads and prevents the cleaning solution from fully wetting the surface. This results in a poorer cleaning result.
Why do deposits remain despite CIP?
Often, the flow rate, temperature or contact time are not correct, or there are spray shadows and dead zones in the system. We will investigate this with you.
Can I use Eco-Nova cleaner in my CIP system?
Yes. As we develop and manufacture our own cleaning agents, we can tailor them to your requirements, such as foaming behaviour, concentration or temperature range. Several of our cleaning agents also hold NSF or ISEGA certificates, for example Meganova.

Our proposal

This cleaner might be suitable

Ultranova is a concentrated, highly alkaline cleaner specially developed for the removal of baked-on residues.

Do you have a similar cleaning problem?

We’ll assess your application and recommend the most promising solution – with a free sample for testing, if you wish.

Read more

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